Degenerative changes in spine and their treatment in modern medical conditions

Spine-is the center of musculoskeletal system, and the same time, important protection for central nervous system (spine cord), which goes along the whole spine. Degenerative changes in spine- are the most often diseases, that have heavy chronic effects. Degenerations, traumas, or other pathologic changes of separate vertebrae’s, discs, also other structures of spine, have negative influence on spine cord functions. That leads to pains or neurologic disorders of different organs and body structures. Degenerative diseases of spine or its traumas often lead to deformation and limitation of segment mobility that usually have progressive character. Mobility of the spine is due to elasticity of intervertebral discs and mobility of facet joints. Degeneration of intervertebral discs or their traumas leads to deformation, destruction, and then to disc’s dysfunction, what after can cause anatomical and functional pathologic changes of the whole spine.

Depends on the pathology, in modern medicine used different appropriate conservative or surgical treatment methods. Conservative treatment methods can lead to the elimination or alleviation of symptoms. Wherein, they can’t stimulate reverse condition or stop the degenerative processes, which is the reason for that pathology. With severe degree of degeneration processes, that accompanied by disc’s or the whole segment’s deformation, where conservative methods are not effective, surgical methods are used, in order to reconstruct intervertebral disc, intervertebral space and segments of spine.

Summing up, one can say, that modern level of medicine doesn’t allow reverse degenerative changes and deformation of spine segments and ensure natural regeneration or reconstruction of different spine structures. Besides, conservative and especially surgical treatment methods can lead to complications and have risks of side effects.

New method RRDSS
In 2004 professor Dr. MD. Arsen Babayan suggested regenerative reconstruction method of vertebral discs that contributed to the beginning of a series of studies in this area. In 2014 MIBRAR® method, developed by professor Babayan, aimed at regenerative reconstruction of all the musculoskeletal structures, first time in the world was successfully applied with unique way on intervertebral discs and facet joints. These surgical interventions performed during degeneration and deformation of intervertebral discs and spine segments, have all the advantages of MIBRAR® method, which confirm the effectiveness of the method.

Course of surgery

Under C-arm X-ray machine control or with help of Cyber-Navi-Hand™ into the intervertebral disc inserted rigid hollow probe with 0,8 mm diameter. With its help necessary micro perforations are performed by MIBRAR® method. Simultaneously, through the canal of the spine cord, in intervertebral disc area, under pressure autologous concentrate is injected.

The process of autologous concentrate implantation is controlled under intraoperative C-arm X-ray regime with simultaneous height increase and shape recovery of the intervertebral disc and space.

Due to implantation, intervertebral disc restores its original height and shape that calculated in advance by programming of Cyber-Navi-Hand™.

This method allows to restore height and shape of intervertebral disc during any degenerative or traumatic deformation; not only during height loss of the disc, but also during displacement of vertebrae (slipped vertebrae / spondylolisthesis, pseudospondylolisthesis, ventrolisthesis, retrolisthesis). Displaced vertebrae restores its original position because of height increase by vertical pressure, arising at the moment of implantation of autologous concentrate, and also tension of stretched anterior and posterior longitudinal ligaments during dilatation of intervertebral space.

To our VIDEO: Regeneration and Reconstruction of Discs and Segments of Spine
In most cases it is possible to restore the height and shape of intervertebral disc, and also of the whole segment already during implantation of autologous concentrate.

After completion of transplantation of regenerative autologous concentrate into intervertebral disc under X-ray or Cyber-Navi-Hand™ control, another intra-articular transplantation of autologous concentrate carries out into facet joints using spinal probe. At the same time micro perforations and irritations of degenerated surface of facet joint are performed. Then autologous concentrate is injected in facet joint. X-ray control allows precisely observe the process of transplantation of the concentrate in facet joint; also clearly seen an increase in the joint space. Autologous transplant promotes reconstruction already during surgery, and also stimulates regenerative processes.

Autologous transplant consists of plasma, derived from venous blood of the patient, enriched with growth factors, anti-inflammatory factors and mesenchymal growth factors, and also from separated highly concentrated lipogenic stem cells, derived from subcutaneous fat tissue of the patient. During transplantation only fresh autologous concentrate is used, derived from venous blood of the patient and his subcutaneous fat tissue, immediately before surgery.

Cyber-Navi-Hand™ help can perform this procedure with special precision and shorter time.

X-ray control doesn’t show soft tissues and inner organs. That’s why planning of the surgical intervention based on MRI images of the patient, where all the body structures and inner organs well represented. Merger of the surgical plan, based on MRI images with X-ray images, done from positioned patient immediately before surgery, helps to avoid collateral dangerous damages of soft tissues and organs during surgery, and also provides reconstruction of spine segments according to a pre calculated plan.

Cyber-Navi-Hand™ especially necessary for severe spine segment deformations, where high accuracy needed and consideration of individual characteristics of deformation.



Indications for use of RRDSS

Method has indications for use for following diseases:

  • Degeneration of the intervertebral discs
  • Acute traumas of intervertebral discs
  • Spondylolisthesis (slipped disc)
  • Pseudospondylolisthesis
  • Instability of spine segments
  • Arthrosis of facet joints
  • Stenosis of spinal canal
  • Foramina stenosis
  • Osteochondrosis
  • Arthrosis of atlantooccipital joint
  • Postoperative complications on intervertebral discs

Reason for intervertebral hernias is as degenerative processes, as acute traumas. During classical surgical interventions, different structures and tissues are removed or damaged, that stabilizing the spine, which in turn leads to destabilization of the spine segments. In this case RRDSS method successfully used. Initial volume of the disc and its stability are restored because of the tissue growth in the regeneration process that leads to the stability of the whole spine segment.

RRDSS indicated for pathologies, that by modern standards are treated with big invasive surgeries and under general anesthesia. In most cases patient gets implantation of intervertebral prosthesis, screws or other artificial implants that often leads to side effect complications, chronic pain syndromes, affection of the nervous system and musculoskeletal apparatus limitations. This in turns negatively affects the patient’s quality of life.

In order to avoid all of the above complications, those surgeries could be replaced by RRDSS method. RRDSS method allows to achieve effective anatomical and stable functional restoration of the intervertebral discs and spine segments, thereby providing an opportunity for unlimited physical exercises and full-fledged maintenance of quality of life.

Surgery results

According to the statistics, patients get rid of complaints and symptoms during one to thirty days after the surgery, although much research shows complete regeneration with complete reconstruction minimum after three month after the surgery. Postoperative regenerative effect can progress over a year. Performed radiological examinations done from three month to year and a half, evidence of a permanent process of improving condition of the intervertebral disc and the whole spine segment.

Comparison of the images made during completion of the surgery and three month after the surgery, showing volume increase of the intervertebral discs, and also complete anatomical spine discs and segments restoration during scoliosis or other vertebrae deformations in sagittal plane, and also during this combination. Following radiological examinations done in half a year, year and year and a half, indicate further progress in recovery of volume and shape of the discs, and also progress in anatomical recovery of the whole segment.

Links to case descriptions:

Diagnosis: Narrowing of intervertebral foramens

Diagnosis: Deforming degeneration of lumbar spine