Knee Arthritis Grade IV

Case: 1.A.KAON.

49 Years (male)


The patient was operated due to the knee osteoarthritis (grade IV) and meniscal tears (abrasion arthroplasty + micro-perforations) in an attempt to rebuild a cartilage. In the two and a half months after the surgery the situation worsened significantly. A progressive knee swelling and knee pain was identified. The patient was not able to walk independently, only with two underarm crutches. The knee was absolutely immobilized. An osteonecrosis has developed.


  • left knee joint in a postoperative condition
  • arthritis (grade IV)
  • bone edema and osteonecrosis of a medial femoral condyle
  • meniscus degeneration


Surgical report dated 29.01.2016:
  • Intraosseous, intrameniscal and intraarticular transplantation of regenerative substances and growth factors concentrate via MIBRAR® method,
  • received that was created from venous blood via CGF technology,
  • also autologous concentrate from abdominal fatty tissue
  • into the medial femoral condyle,
  • medial meniscus and
  • joint gap of the left knee joint.


Images description:

MIBRAR® surgery on the left knee joint:


The images 1, 3, 5 and 7 dated 12.01.2016

MRI images on different levels correspond to the preoperative status and show osteonecrosis, bone edema, meniscus degeneration and massive fluid retention.


Images 2, 4, 6 and 8 dated 02.06.2017

MRI images on different levels correspond to the postoperative status in 18 months after the MIBRAR® surgery. Osteonecrosis and bone edema can no longer be seen, a complete regeneration of meniscus and cartilage layer have been noted.


Surgery result:

All the symptoms disappeared within 4 weeks after the surgery, the patient can move freely without crutches. Within 8 weeks after the surgery the patient was able to do a competitive sport without any problems, up to the present day the patient is free of complaints.